Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Polym Bull

Search In Journal Title:

Abbravation: Polymer Bulletin

Search In Journal Abbravation:

Publisher

Springer Berlin Heidelberg

Search In Publisher:

DOI

10.1016/0375-9601(87)90554-8

Search In DOI:

ISSN

1436-2449

Search In ISSN:
Search In Title Of Papers:

Characterization and evaluation of siderophoreloa

Authors: Sita Lakshmi Thyagarajan Giriprasath Ramanathan Sivakumar Singaravelu S Kandhasamy P T Perumal Uma Tiruchirapalli Sivagnanam
Publish Date: 2016/10/27
Volume: 74, Issue: 6, Pages: 2349-2363
PDF Link

Abstract

Wound healing is a dynamic interactive process involving soluble mediators blood cells and ECM Extra Cellular Matrix Significant changes in ECM degradation may lead to delayed wound healing Matrix metalloproteinase MMPs are a family of endopeptidases that function in the remodeling of ECM proteins wherein overexpression of these MMPs is capable of degrading ECM and biologically active proteins at the wound sites Regulations of these MMPs at the wound sites hasten the wound healing The aim of this study is to release the product which inhibits MMPs and as well as to reduce the bacterial load on the wound site in a controlled manner Siderophore organic ion chelator was isolated from Pseudomonas aeruginosa strain S1 and purified through various chromatographic techniques used as for dual purpose in this study The design and development of wound dressing through a carrier system such as microspheres are indeed a novel approach to promote healing The design in this study includes preparation of microspheres using gelatin and siderophore SGM The morphological characteristics of the prepared microspheres were found to be rigid highly porous and their mean diameter of five siderophoreloaded microspheres formulations was between 70 ± 052 and 253 ± 0 31 µm The drug release of the prepared samples was fast and entrapment efficiency was about 93 at 24 h in Batch 3 Gelatinmodified microspheres were found to be nontoxic and a good biocompatible product which was assessed using NIH 3T3 fibroblast cell lines The overall study suggests that SGM microspheres could be used as a potent tool for MMP inhibitor for wound healing applicationsThe author gratefully acknowledges financial support for this work through the grants awarded by the Department of Science and Technology DST New Delhi India SR/WOSA/LS375 Financial support from CSIR under Translational Project OLP09/TRP is acknowledged

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. Plasticization of amorphous polystyrene by volatile organic compounds
  2. Synthesis and characterization of pH-sensitive superabsorbent hydrogels based on sodium alginate- g -poly(acrylic acid- co -acrylamide) obtained via an anionic surfactant micelle templating under microwave irradiation
  3. Silane treatment of magnetite filler and its effect on the properties of magnetite-filled epoxy thin-film composites
  4. Removal of acidic dye from aqueous solutions using poly(DMAEMA–AMPS–HEMA) terpolymer/MMT nanocomposite hydrogels
  5. Synthesis and properties of silk sericin- g -poly(acrylic acid-co-acrylamide) superabsorbent hydrogel
  6. Acanthus ebracteatus Vahl. extract-loaded cellulose acetate ultrafine fibers as a topical carrier for controlled-release applications
  7. 3- O -Propyl cellulose: cellulose ether with exceptionally low flocculation temperature
  8. Evaluation of ion exchange resins for removal and recuperation of ammonium–nitrogen generated by the evaporation of landfill leachate
  9. Helical Polymers from Optically Active Epoxides with Bulky Pendants
  10. Use of polystyrene sulfonate produced from waste plastic cups as an auxiliary agent of coagulation, flocculation and flotation for water and wastewater treatment in Municipal Department of Water and Wastewater in Uberlândia-MG, Brazil
  11. Dielectric properties of epoxy composites with modified multiwalled carbon nanotubes
  12. Antimicrobial activity from polymeric composites-based polydimethylsiloxane/TiO 2 /GO: evaluation of filler synthesis and surface morphology
  13. Thermal stability and thermal degradation kinetics (model-free kinetics) of nanocomposites based on poly (lactic acid)/graphene: the influence of functionalization
  14. A novel hydrophobically associating polyampholytes of poly(AM/AA/AMQC12): preparation, characterization, and solution properties
  15. Influence of the multi-functional epoxy monomers structure on the electro-optical properties and morphology of polymer-dispersed liquid crystal films
  16. Heavy metal ions removal through poly(acrylamide- co -methacrylic acid) resin
  17. Study of structure and properties of polypropylene microporous membrane by hot stretching
  18. Water resistance and thermal stability of hybrid lignocellulosic filler–PVC composites
  19. Polyacrylate/silica hybrids prepared by emulsifier-free emulsion polymerization and the sol–gel process
  20. Chelating water-soluble polymers associated with ultrafiltration membranes for metal ion removal
  21. Combining control of branching and sulfonation in one-pot synthesis of random sulfonated polyarylethersulfones: effects on thermal stability and water retention
  22. Effect of organic modifier type of montmorillonite on the poly (butyl acrylate- co -methyl methacrylate)/montmorillonite nanocomposite
  23. Structure and Mechanical Properties of Shape Memory Polyurethane Based on Hyperbranched Polyesters
  24. Electrophilic Aromatic Functionalization of Phenolic Photoresist Polymers
  25. Effect of nano-ZnO-supported 13X zeolite on photo-oxidation degradation and antimicrobial properties of polypropylene random copolymer
  26. A convenient laboratory preparation of aromatic polycarbonate
  27. Synthesis and characterization of highly soluble and thermally stable new polyimides based on 3,5-diamino benzoyl amino phenyl-14H-dibenzo[a,j]xanthene
  28. Step-Growth Polymerization of 4-(1-Naphthyl)-1,2,4-triazolidine-3,5-dione with Diisocyanates
  29. Synthesis of novel branched UV-curable methacrylate copolymer and its application in negative photoresist
  30. Step-Growth Polymerization of 4-(1-Naphthyl)-1,2,4-triazolidine-3,5-dione with Diisocyanates
  31. Synthesis of the Optically Active Polymer Consisting of Chiral Phosphorus Atoms and p -Phenylene-ethynylene Units
  32. Using Agrawal integral equation and thermogravimetric analysis (TGA) to study the pyrolysis kinetics of nanocomposites of polybenzoxazine and exfoliated montmorillonite from a mono-functionalized azide polyhedral oligomeric silsesquioxane and click chemistry
  33. Swelling-assisted reduction of chitosan molecular weight in the solid state using hydrogen peroxide
  34. Functional copolymer/organo-MMT nanoarchitectures: self-assembled core-shell morphology of poly(maleic anhydride- alt -α-olefin)/organo-MMT nanocomposites
  35. Synthesis, characterisation and flame, thermal and electrical properties of poly ( n -butyl methacrylate)/titanium dioxide nanocomposites
  36. Influence of styrene–ethylene–butylene–styrene (SEBS) copolymer on the short-term static mechanical and fracture performance of polycarbonate (PC)/SEBS blends
  37. Dye-sensitized solar cells based on electrospun poly(vinylidenefluoride- co -hexafluoropropylene) nanofibers
  38. Synthesis of star polymethyl acrylate by SET-LRP at ambient temperature
  39. Synthesis of star polymethyl acrylate by SET-LRP at ambient temperature
  40. Treating any polymer dissolved in water as polymer presenting a draining effect
  41. Synthesis and super-swelling behavior of a novel protein-based superabsorbent hydrogel
  42. The effect of stereoregularity on the thermal behavior of poly(methacrylic acid)s
  43. Polylactic acid and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) nano and microparticles for packaging bioplastic composites
  44. Structure analysis and thermosensitive properties of copolymers prepared from 2-ethyl-2-oxazoline and 2-(4-aminophenyl)-2-oxazoline
  45. Synthesis of Poly(alcohol)s by Hydroboration/Oxidation of Poly(methylallene) Prepared by π-Allylnickel-Catalyzed Living Coordination Polymerization
  46. Solution properties and flocculation of hydrophobically associating cationic fluorinated polyacrylamide
  47. Analysis of dynamic oscillatory rheological properties of PP/EVA/organo-modified LDH ternary hybrids based on generalized Newtonian fluid and generalized linear viscoelastic approaches
  48. New functional copolymers of N -acryloyl- N ′-methyl piperazine and 2-hydroxyethyl methacrylate: synthesis, determination of reactivity ratios and swelling characteristics of gels
  49. Effects of crystallization temperature and spherulite size on cracking behavior of semi-crystalline polymers
  50. Physicochemical characteristics of poly(2-ethyl-2-oxazoline)/poly(ε-caprolactone) block copolymer micelles in water
  51. Thermal and mechanical stabilities of composite films from thiadiazol bearing poly(amide-thioester-imide) and multiwall carbon nanotubes by solution compounding
  52. Synthesis and study of the effect of carboxyvinyl group position on the properties of polyamides. Crosslinked polymers
  53. Structure–rheology relationship in complex quaternized polysulfones/solvent/nonsolvent systems
  54. Polymeric membranes composed of polystyrenes tethering amino acids for preferential CO 2 separation over H 2
  55. Surface functionalized carbon nanotubes and its effects on the mechanical properties of epoxy based composites at cryogenic temperature
  56. The morphology and mechanical properties of PP/EPDM/nano-CaCO 3 composites: effect of initial mixing state
Search Result: