Authors: Camila F Correa Luiza R Santana Ricardo M Silva Bruno S Noremberg Rafael G Lund Juliana S Ribeiro Fabiana V Motta Mauricio R D Bomio Rubens M Nascimento Neftali L V Carreño
Publish Date: 2016/11/04
Volume: 74, Issue: 6, Pages: 2379-2390
Abstract
Antimicrobial substances may be used to reduce hospital infections and inhibit food contamination thus ensuring the safety and well being of humans The objective of this study was to evaluate the antimicrobial activity of the polymeric nanocomposites polydimethylsiloxane PDMS embedded with two types of fillers based on titanium dioxide commercial TiO2 P25 versus TiO2 via facile Microwaveassisted hydrothermalMAH synthesis and graphene oxide GO The nanocomposites were prepared using different compositions concentrations and functionalizations PDMS/TiO2/GO PDMS/TiO2 and PDMS/GO The antimicrobial activity of the samples was evaluated for different treatments on Candida albicans Staphylococcus aureus and Enterococcus faecalis by a modified direct contact test mDCT The samples were also evaluated on surface morphology and the roughness as a function of active particles insertion by atomic force microscopy AFM Most of the PDMS films whose polymer was embedded with GO and hydrothermal TiO2 showed the highest inhibition growth of bacteria and Candida over 24 h After 24 h F J and H samples showed the best antibacterial activity whereas E showed the best antifungal activity The results indicated that the nanocomposites PDMS/GO/TiO2MAH and PDMS/GO sample enhanced antimicrobial activity in the treatments tested therefore they were functional for contaminant reduction
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