Authors: Maria Vella Jonathan Duckett Maya Basu
Publish Date: 2008/01/30
Volume: 19, Issue: 7, Pages: 961-964
Abstract
This aim of this study was to determine the longterm persistence with duloxetine in a cohort of women treated for stress incontinence and any alternative treatments undertaken Two hundred twentyeight women prescribed duloxetine were initially reviewed after 4 weeks of treatment Women continuing therapy were reassessed at 4 and 6 months and 1 year with a review of all treatments after 1 year At each visit they were asked about persistence with duloxetine reasons for discontinuation and any alternative treatments Seventyone 31 women continued beyond 4 weeks of treatment and twentysix 12 were taking duloxetine 4 months later 23 10 at 6 months and 21 9 at 1 year One year later 187 82 women had a tensionfree vaginal tape operation TVT The majority of women discontinued because of side effects 56 or lack of efficacy 33 Few women persevere with duloxetine beyond 4 months One year later the majority of women had a TVT
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