Authors: Hideaki Tokuyama Hiroshi Sumida Akifumi Kanehara Susumu Nii
Publish Date: 2008/11/19
Volume: 287, Issue: 1, Pages: 115-
Abstract
Stimulisensitive porous hydrogels prepared with an emulsion templating method developed by the authors are potentially applicable in the medical and pharmaceutical fields thermosensitive Nisopropylacrylamide NIPA hydrogels having randomly distributed spherelike cavities have been prepared by the polymerization in an aqueous phase in an oilinwater O/W emulsion followed by the washing of oil oleyl alcohol microdroplets The surfactant plays a dominant role in the preparation of porous hydrogels and the pore size This study concerns with the surfactant effects on the stability of pregel O/W emulsions The porous NIPA hydrogels were successfully prepared using the surfactants forming the stable emulsion and their internal structures and swelling properties were characterized The O/W emulsions and the porous hydrogels prepared using various amounts of oil and surfactant were characterized The information obtained serves for preparation of porous hydrogels having suitable porous structure for their applicationsThe authors thank Takemoto oil fat for the supply of surfactants and Kohjin for Nisopropylacrylamide The authors wish to acknowledge the supports of a GrantinAid for Young Scientists B from JSPS Japan Society for the Promotion of Science Grant No 19760534
Keywords: