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Title of Journal: neurotox res

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Abbravation: Neurotoxicity Research

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Springer New York

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DOI

10.1007/s00769-008-0483-6

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1476-3524

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Neurophysiological effects of botulinum toxin type

Authors: G Abbruzzese A Berardelli
Publish Date: 2009/03/07
Volume: 9, Issue: 2-3, Pages: 109-114
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Abstract

Botulinum toxin type A BoNTA acts peripherally by inhibiting acetylcholine release from the presynaptic neuromuscular terminals thus weakening muscle contraction and its clinical benefit depends primarily on the toxin’ peripheral action In addition to acting directly at the neuromuscular junction the toxin alters sensory inputs to the central nervous system thus indirectly inducing secondary central changes Some of the longterm clinical benefits of BoNTA treatment may also reflect plastic changes in motor output after the reorganization of synaptic density

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  2. The Kynurenine Pathway and Inflammation in Amyotrophic Lateral Sclerosis
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  5. Glutamate Carboxypeptidase Inhibition Reduces the Severity of Chemotherapy-Induced Peripheral Neurotoxicity in Rat
  6. Erratum to: Neuroprotective Effect of the Endogenous Amine 1MeTIQ in an Animal Model of Parkinson’s Disease
  7. The Effect of Adenosine A 2A Receptor Antagonists on Hydroxyl Radical, Dopamine, and Glutamate in the Striatum of Rats with Altered Function of VMAT2
  8. Reciprocal Induction Between α-Synuclein and β-Amyloid in Adult Rat Neurons
  9. Developmental Exposure to Very Low Levels of Ethynilestradiol Affects Anxiety in a Novelty Place Preference Test of Juvenile Rats
  10. Muscle fiber orientation in muscles commonly injected with botulinum toxin: An anatomical pilot study
  11. Chronic Pretreatment with Acetyl- l -Carnitine and ±DL-α-Lipoic Acid Protects Against Acute Glutamate-Induced Neurotoxicity in Rat Brain by Altering Mitochondrial Function
  12. Evaluation of the Neurotoxic/Neuroprotective Role of Organoselenides Using Differentiated Human Neuroblastoma SH-SY5Y Cell Line Challenged with 6-Hydroxydopamine
  13. Organochalcogens Inhibit Mitochondrial Complexes I and II in Rat Brain: Possible Implications for Neurotoxicity
  14. Persistence of Long-Term Memory Storage: New Insights into its Molecular Signatures in the Hippocampus and Related Structures
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