Authors: Byoung Seok Ye Young Dae Kim Hyo Suk Nam Hye Sun Lee Chung Mo Nam Ji Hoe Heo
Publish Date: 2010/08/15
Volume: 9, Issue: 4, Pages: 571-579
Abstract
Lesions in the cerebellum produce various symptoms related to balance and motor coordination However the relationship between the exact topographical localization of a lesion and the resulting symptoms is not well understood in humans In this study we analyzed 66 consecutive patients with isolated cerebellar infarctions demonstrated on diffusionweighted magnetic resonance imaging We identified the involved lobules in these patients using a crossreferencing tool of the picture archiving and communication system and we investigated the relationships between the sites of the lesions and specific symptoms using χ 2 tests and logistic regression analysis The most common symptoms in patients with isolated cerebellar infarctions were vertigo 87 and lateropulsion 82 Isolated vertigo or lateropulsion without any other symptoms was present in 38 of patients On the other hand limb ataxia was a presenting symptom in only 40 of the patients Lateropulsion vertigo and nystagmus were more common in patients with a lesion in the caudal vermis Logistic regression analysis showed that lesions in the posterior paravermis or nodulus were independently associated with lateropulsion Lesions in the nodulus were associated with contralateral pulsion and involvement of the culmen was associated with ipsilateral pulsion and isolated lateropulsion without vertigo Nystagmus was associated with lesions in the pyramis lobule while lesions of the anterior paravermis were associated with dysarthria and limb ataxia Our results showed that the cerebellar lobules are responsible for producing specific symptoms in cerebellar stroke patients
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