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Title of Journal: Radiol med

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Abbravation: La radiologia medica

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Publisher

Springer Milan

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DOI

10.1002/ar.1091850103

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ISSN

1826-6983

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Classification of noncalcified coronary atheroscle

Authors: E Maffei K Nieman C Martini O Catalano S Seitun T Arcadi R Malagò A Rossi A Clemente N R Mollet F Cademartiri
Publish Date: 2011/11/17
Volume: 117, Issue: 2, Pages: 230-241
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Abstract

Thirty patients men 25 age 59±8 years with stable angina underwent arterial and delayed CTCA At sites of atherosclerotic plaque attenuation values HU were measured within the coronary lumen noncalcified and calcified plaque material and the surrounding epicardial fat Based on the measured CT attenuation values coronary plaques were classified as lipid rich attenuation value below the threshold or fibrous attenuation value above the threshold using 30HU 50HU and 70HU density thresholdsOne hundred and sixtyseven plaques 117 mixed and 50 noncalcified were detected and assessed The attenuation values of mixed plaques were higher than those of exclusively noncalcified plaques in both the arterial 1483±731 HU vs 1062±579 HU and delayed 1114±505 HU vs 644±434 HU phases p001 Using a 50HU threshold 12 72 plaques would be classified as lipid rich on arterial scan compared with 28 17 on the delayedphase scan Reclassification of these 16 96 plaques from fibrous to lipid rich involved 4/30 13 patientsTrenta pazienti maschi 25 età 59±8 anni con angina stabile sono stati sottoposti a CTCA in fase arteriosa e tardiva Nei segmenti con aterosclerosi coronarica è stata misurata l’attenuazione HU del lume coronarico delle componenti calcifica e non calcifica delle placche aterosclerotiche e del tessuto adiposo epicardico adiacente Sulla base delle attenuazioni misurate le placche sono state classificate come lipidiche valori di attenuazione al di sotto della soglia o fibrose valori di attenuazione al di sopra della soglia utilizzando 30 HU 50 HU e 70 HU come soglie di densitàSono state rilevate e valutate 167 placche 117 miste e 50 non calcifiche I valori di attenuazione della placche miste è risultato maggiore di quello delle placche esclusivamente non calcifiche sia in fase arteriosa 1483±731 HU vs 1062±579 HU che in fase tardiva 1114±505 HU vs 644±434 HU p001 Utilizzando una soglia di 50 HU 12 72 placche sarebbero state classificate come lipidiche nella fase arteriosa contro 28 17 nella fase tardiva La riclassificazione di queste 16 96 placche da fibrose a lipidiche è avvenuta in 4/30 13 pazienti

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