Authors: Antonio Orlacchio Francesca Bolacchi Fabrizio Chegai Alberto Bergamini Elisa Costanzo Costantino Del Giudice Mario Angelico Giovanni Simonetti
Publish Date: 2013/11/26
Volume: 119, Issue: 5, Pages: 298-308
Abstract
Thirty patients with single HCC ≤4 cm in diameter were randomly assigned to one of two treatments 15 patients were treated with PLA using a multifibre system connected to a neodymium yttrium–aluminium–garnet laser source 15 patients were treated with RFA using an expandable needle electrode Patients were followed up for up to 12 monthsA complete response was obtained in 87 lesions treated with PLA and in 93 lesions treated with RFA p = ns The overall local recurrencefree survival rates at 3 6 and 12 months were comparable However a higher rate of recurrence was observed in the PLA group for lesions ≥21 mm p = 00081 A postablation syndrome was documented in 13 patients 1 PLA 12 RFA Tumour necrosis factorα was significantly higher in the RFA group p 005
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