Authors: Tolga Ertekin Niyazi Acer Semra Içer Ahmet T Ilıca
Publish Date: 2012/11/10
Volume: 35, Issue: 4, Pages: 301-309
Abstract
The subcortical brain structures are associated with other structures of nervous system therefore they have major influence on sensory–motor limbic and cognitive information processing Magnetic resonance imaging provides a detailed knowledge of normal and diseased anatomical structures for medical research The aim of the current study was to compare the volumes of subcortical brain structures and determine the probable volumetric asymmetry in healthy subjects using stereological pointcounting and semiautomatic segmentation methodsWe did not find any significant differences among the subjects with respect to gender using both methods This study showed no significant asymmetry in subcortical structures according to methods Also no significant difference was found between pointcounting and semiautomated segmentation methods for the volumes of subcortical structures p 005From these results it can be concluded that the semiautomated segmentation method and stereological technique can be used for reliable volume estimation of subcortical structures However the stereological method takes less time than semiautomated segmentation it is simple reliable and inexpensive Further studies are required with larger samples in order to support these data
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