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Title of Journal: Knee Surg Sports Traumatol Arthrosc

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Abbravation: Knee Surgery, Sports Traumatology, Arthroscopy

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Publisher

Springer Berlin Heidelberg

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DOI

10.1006/viro.2001.0926

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ISSN

1433-7347

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The influence of sex hormones on anterior cruciate

Authors: Lazar Stijak Marko Kadija Vuk Djulejić Milan Aksić Nataša Petronijević Dubravka Aleksić Vidosava Radonjić Marko Bumbaširević Branislav Filipović
Publish Date: 2014/08/27
Volume: 23, Issue: 12, Pages: 3578-3584
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Abstract

The purpose of this study is to determine the difference in the concentrations of testosterone 17β estradiol and progesterone between male patients with and without ACL rupture as well as the possible effect of these hormones on generalized joint laxityMale subjects with noncontact knee joint injury were included in this study Two groups were formed the examined group consisting of subjects with ACL rupture and the control group consisting of patients without ACL rupture After this the patients from these two groups were paired off on the basis of three factors level of professional involvement in sports including the type of sports activity left or right side of the body and the age of the subjects In the end there were 29 pairs 58 subjects The concentration of sex hormones was determined from saliva specimens with the aid of the Salimetrics enzyme immunoassay The testing of generalized joint laxity was performed with the aid of the “laxity score” according to Beighton et alSubjects with ACL rupture have highly statistically significantly greater concentrations of testosterone p  001 statistically significantly greater concentrations of 17β estradiol p  005 and a highly statistically significantly greater generalized joint laxity score than subjects with an intact ACL p  001Increased concentrations of testosterone or 17β estradiol may be a risk factor leading to ACL rupture Also generalized joint laxity may be a factor leading to ACL rupture but none of the monitored hormones can be set down as the cause of its existence Young male athletes with higher concentrations of testosterone and greater hyperelasticity should plan preventive programs of physiotherapy for ACL preservation since they present a vulnerable group susceptible to ACL rupture

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