Authors: Eugene Sebastian J Nidiry Girija Ganeshan A N Lokesha
Publish Date: 2015/12/06
Volume: 49, Issue: 9, Pages: 624-626
Abstract
Hexane ethyl acetate and methanol extractives of Coleus forskohlii roots exhibit mycelial growth inhibition of Colletotrichum gloeosporioides and spore germination inhibition of Alternaria solani Forskolin a diterpene present in C forskohlii exhibit dose dependent spore germination inhibition of A solani this being the first report on the antifungal activity of this compound Estimation of forskolin in the extractives by HPLC showed that while hexane extractive contained 39 forskolin and ethyl acetate extractive contained 46 forskolin while the methanol extractive did not contain forskolin The results clearly show that forskolin is one of the antifungal compounds present in the plant
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