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Title of Journal: Russ Chem Bull

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Abbravation: Russian Chemical Bulletin

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Springer US

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1573-9171

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Effect of glycyrrhizic acid on hemolysis of red bl

Authors: O Yu Selyutina N E Polyakov D V Korneev B N Zaitsev
Publish Date: 2015/02/28
Volume: 63, Issue: 5, Pages: 1201-1204
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Abstract

Due to amphiphilic properties glycyrrhizic acid is capable of forming watersoluble conjugates with a wide variety of hydrophobic pharmaceutical compounds This results in a significant reduction in the therapeutic dose of the drugs To enlighten the molecular and cellular mechanisms of the observed effects the influence of glycyrrhizic acid on the properties of cell membranes was studied by physical methods Glycyrrhizic acid was found to increase the elasticity of human erythrocyte membranes and slow down the process of hemolysis


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