Authors:
Publish Date: 1992/10/01
Volume: 6, Issue: 10, Pages: 519-522
Abstract
To evaluate organ recovery during mechanical assistance respiratoryhepatic and renal function parameters of 40 patients who underwentbridgetotransplant procedures were reviewed retrospectively Mechanicalcirculatory support was indicated if the hemodynamic and clinical statusdeteriorated despite pharmacotherapy with catecholamines vasodilators andintravenous use of the phosphodiesterase inhibitor enoximone Sequelae ofcardiogenic shock such as renal hepatic and respiratory insufficiency werenot considered a contraindication for mechanical support The analysis ofpreimplant data such as serum creatinine liver enzymes and pulmonary gasexchange did not identify any predictive indicator of irreversible organdamage Functional recovery of preexisting respiratory hepatic and renaldysfunction was found in 91 90 and 85 respectively Subsequenttransplantation however was affected by the number of failing organsprior to mechanical support Of 17 patients with isolated organ failureprior to assist 14 82 were transplanted By contrast 9 75 of 12with combined failure of two organs and only 6 54 of 11 patients withclinical patterns of three failing organ systems received transplants Inall patients who underwent successful transplantation transplantabilitywas associated with rapid organ recovery within 10 to 15 days afterinitiating mechanical assistance
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