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Title of Journal: Eur J Appl Physiol

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Abbravation: European Journal of Applied Physiology

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Springer-Verlag

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DOI

10.1002/chin.198941047

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ISSN

1439-6327

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Effects of shortterm corticoid ingestion on food

Authors: N Rieth L Jollin B Le Panse AM Lecoq A Arlettaz J De Ceaurriz K Collomp
Publish Date: 2008/11/05
Volume: 105, Issue: 2, Pages: 309-
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Abstract

In order to test the hypothesis that shortterm corticoid intake alters food intake body composition and adipokines secretion in healthy volunteers with regular sport practice nutrient intake was assessed in eight male athletes with and without prednisolone PRED 60 mg/day for 1 week ingestion in a random double blind crossover design Body weight body composition adipokines ie leptin adiponectin and TNFα insulin and blood glucose were determined before and at the end of each treatment PRED did not induce any significant change in body weight body composition or food intake Insulin and TNFα were not significantly altered with PRED compared to placebo but blood glucose leptin and adiponectin concentrations at rest appear significantly increased after PRED treatment P  005 Our data show that 1 week glucocorticoid treatment does not promote obesity in recreationally trained men but further studies are necessary to understand its effects on the metabolically active hormones leptin and adiponectinThis project has been carried out with the support of WADA World Antidoping Agency The authors wish to express their gratitude to the subjects for their dedicated performance In addition we likewise thank the CHR of Orléans Nathalie Crépin Sandra Ferary Patrick Guenon Nicole Chevrier for their assistance

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