Authors: Małgorzata M Posmyk Renata Kontek Krystyna M Janas
Publish Date: 2008/02/09
Volume: 30, Issue: 4, Pages: 481-491
Abstract
Natural phenolic compounds phenolic acids flavonoids tannins lignans present in food of plant origin are in the focus of interest due to their prevalence properties and biological activity The aim of the presented work was to investigate antioxidant and antigenotoxic effects of the anthocyaninrich extract from red cabbage leaves Brassica oleracea rubrum on the changes induced by toxic Cu2+ concentrations MeOH extract from red cabbage containing anthocyanin ATH and phenolic acid derivatives exhibited strong antioxidant properties Cu2+ decreased mitotic index MI and inhibited proliferative activity of Vicia faba root meristematic cells The morphology of mitotic chromosomes was changed “erosion” and pulverization might result from Cu2+ highcytotoxicity Numerous micronuclei chromatid bridges and lagging/lost chromosomes were found in the meristematic cells of V faba which indicate the clastogenic effect of Cu2+ The application of the ATHrich extract lowered the number of disturbances induced by Cu2+ The positive role of the ATHrich red cabbage extract will be discussed
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