Authors: Kyung Hee Yi Jin Soon Hwang Eun Young Kim Jun Ah Lee Dong Ho Kim Jung Sub Lim
Publish Date: 2013/07/06
Volume: 32, Issue: 3, Pages: 281-289
Abstract
Bone acquisition failure during growth or low bone mineral density BMD in childhood and adolescence might increase future osteoporosis risk To identify these children and adolescents appropriate reference values are necessary The robust reference values must be community based as well as sex age and ethnicity specific In addition body size adjustment is necessary because individuals demonstrate different body sizes and different tempos of growth which affect measured BMD We aimed to provide reference data with body size adjustment of Korean children and adolescents We used dualenergy Xray absorptiometry data of 1650 subjects aged 10–20 years 788 female from the Korea National Health and Nutrition Examination Survey 2009–2010 The BMD of each region of interest ROI including the lumbar spine total body less head total body and femoral neck were obtained We calculated the mean and percentiles for each ROI Because height and weight variations were high and correlated independently with BMD within the same age group we developed equations to calculate the “predicted BMD Z score” Although 128–179 of subjects with short stature showed a low measured BMD Z score depending on the measured site only 26 of those of short stature had a low adjusted BMD Z score after applying the predicted BMD Z score We also compared the BMD of children and adolescents of other ethnicities using the same device This study provided robust reference values for the assessment and monitoring of bone health in Korean children and adolescents Additionally it extended the knowledge of bone acquisition in Asian children and adolescents
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