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Title of Journal: J Bone Miner Metab

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Abbravation: Journal of Bone and Mineral Metabolism

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Springer Japan

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DOI

10.1016/0079-6786(90)90001-v

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ISSN

1435-5604

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Is the negative relationship between obesity and b

Authors: Wankyo Chung Jongseok Lee OhkHyun Ryu
Publish Date: 2013/10/11
Volume: 32, Issue: 5, Pages: 505-513
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Abstract

Obesity and osteoporosis are two important body composition problems with increasing prevalences in aged populations Traditionally obesity has been regarded as being beneficial to bone health However the protective effect of obesity on osteoporosis has been questioned In some recent studies obesity as defined by percentage body fat was regarded as a risk factor for osteoporosis The purpose of this study was to 1 evaluate the effect of waist circumference a surrogate measure for abdominal obesity on bone mineral content BMC and 2 examine whether the effect of waist circumference increases with advancing age The study population is made up of women aged over 45 years who completed the body composition and bone mineral density examinations in the fifth Korea National Health and Nutrition Examination Survey in 2010 Subjects who take estrogen or are under medical treatment for osteoporosis were excluded Stroke patients are also excluded Femoral neck totalhip and wholebody BMC were measured by dualenergy Xray absorptiometry A total of 1434 subjects were included in the analysis Waist circumference was negatively associated with BMC in all tested regions after correction for weight menopausal status smoking drinking and exercise In addition the negative association between waist circumference and BMC in the femoral neck and total hip increases with age after correction for confounding factors showing an interaction effect between waist circumference and age on BMC In conclusion this study shows that the negative relationship between waist circumference and BMC in the femoral neck and total hip is greater for older women


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  1. Reference values for bone mineral density according to age with body size adjustment in Korean children and adolescents
  2. Changes in bone resorption markers among Japanese patients with postmenopausal osteoporosis treated with alendronate and risedronate
  3. Effects of eldecalcitol on bone and skeletal muscles in glucocorticoid-treated rats
  4. Wnt signaling in bone metabolism
  5. Effect of monthly intravenous ibandronate injections on vertebral or non-vertebral fracture risk in Japanese patients with high-risk osteoporosis in the MOVER study
  6. In vivo expression and regulation of genes associated with vascularization during early response of sutures to tensile force
  7. Effect of osteoporosis medication on changes in bone mineral density and bone turnover markers after 24-month administration of daily teriparatide: comparison among minodronate, raloxifene, and eldecalcitol
  8. Teriparatide is safe and effectively increases bone biomarkers in institutionalized individuals with osteoporosis
  9. Actin and microtubule cytoskeletons of the processes of 3D-cultured MC3T3-E1 cells and osteocytes
  10. Effects of transgenic Pit-1 overexpression on calcium phosphate and bone metabolism
  11. Inorganic polyphosphate differentiates human mesenchymal stem cells into osteoblastic cells
  12. Anti-cancer IAP antagonists promote bone metastasis: a cautionary tale
  13. Anti-cancer IAP antagonists promote bone metastasis: a cautionary tale
  14. Low-energy diaphyseal femoral fractures associated with bisphosphonate use and severe curved femur: a case series
  15. Disability for daily living is a predictor for joint replacement in patients with end-stage knee osteoarthritis
  16. Skeletal deterioration following ovarian failure: can some features be a direct consequence of estrogen loss while others are more related to physical inactivity?
  17. Phosphate enhances Fgf23 expression through reactive oxygen species in UMR-106 cells
  18. Effects of losartan treatment on the physicochemical properties of diabetic rat bone
  19. IL-6 negatively regulates osteoblast differentiation through the SHP2/MEK2 and SHP2/Akt2 pathways in vitro
  20. Relationship between autonomic nervous system activity and bone mineral density in non-medicated perimenopausal women
  21. Captopril improves osteopenia in ovariectomized rats and promotes bone formation in osteoblasts

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