Authors: Cheryl L Grady Douglas D Garrett
Publish Date: 2013/09/06
Volume: 8, Issue: 2, Pages: 274-283
Abstract
Recent work in neuroscience supports the idea that variability in brain function is necessary for optimal brain responsivity to a changing environment In this review we discuss a series of functional magnetic resonance imaging fMRI studies in younger and older adults to assess agerelated differences in variability of the fMRI signal This work shows that momenttomoment brain signal variability represents an important “signal” within what is typically considered measurementrelated “noise” in fMRI This accumulation of evidence suggests that moving beyond the mean will provide a complementary window into agingrelated neural processes
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