Authors: Erica Shields Hammer Marilyn J Cipolla
Publish Date: 2015/07/01
Volume: 17, Issue: 8, Pages: 64-
Abstract
Preeclampsia is a hypertensive multisystem disorder of pregnancy that affects several organ systems including the maternal brain Cerebrovascular dysfunction during preeclampsia can lead to cerebral edema seizures stroke and potentially maternal mortality This review will discuss the effects of preeclampsia on the cerebrovasculature that may adversely affect the maternal brain including cerebral blood flow CBF autoregulation and bloodbrain barrier disruption and the resultant clinical outcomes including posterior reversible encephalopathy syndrome PRES and maternal stroke Potential longterm cognitive outcomes of preeclampsia and the role of the cerebrovasculature are also reviewed
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