Journal Title
Title of Journal: Curr Hypertens Rep
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Abbravation: Current Hypertension Reports
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Authors: Gwendolyn K Davis Ashley D Newsome Norma B Ojeda Barbara T Alexander
Publish Date: 2017/02/23
Volume: 19, Issue: 2, Pages: 13-
Abstract
It is wellestablished that the agerelated increase in blood pressure is augmented after menopause Yet the prevalence of hypertension is enhanced in low birth weight women relative to normal birth weight counterparts by 60 years of age suggesting that adverse influences during fetal life heighten cardiovascular risk in later lifeA changing hormonal milieu may contribute to increased cardiovascular risk that occurs after the menopausal transition Low birth weight is associated with early age at menopause A recent study indicates that a shift towards testosterone excess following early reproductive senescence may contribute to the etiology of agedependent increases in blood pressure in a rodent model of low birth weightDr Alexander is supported by the National Institutes of Health HL074927 HL51971 P20GM104357 and the American Heart Association GRNT19900004 Ms Davis and Ms Newsome are supported by NIH T32HL105324 and F30DK112718 respectively Dr Ojeda has no disclosures
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