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Title of Journal: Curr Hypertens Rep

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Abbravation: Current Hypertension Reports

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Springer US

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10.1002/dvdy.20533

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1534-3111

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Vasopressin Receptor Antagonists

Authors: Biff F Palmer
Publish Date: 2015/01/22
Volume: 17, Issue: 1, Pages: 1-
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Abstract

Arginine vasopressin AVP is the principal hormone involved in regulating the tonicity of body fluids Less appreciated is the role that AVP plays in a variety of other physiologic functions including glucose metabolism cardiovascular homeostasis bone metabolism and cognitive behavior AVP receptor antagonists are now available and currently approved to treat hyponatremia There is a great deal of interest in exploring the potential benefits that these drugs may play in blocking AVPmediated effects in other organ systems The purpose of this report is to provide an update on the expanding role of AVP receptor antagonists and what disease states these drugs may eventually be used for


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