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Title of Journal: Pediatr Radiol

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Abbravation: Pediatric Radiology

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Springer Berlin Heidelberg

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DOI

10.1007/bf02839804

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1432-1998

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Nonsclerotic bone involvement in Erdheim–Chester

Authors: Theresa V White Nicholas C Silvester Hansel J Otero
Publish Date: 2016/03/30
Volume: 46, Issue: 9, Pages: 1345-1349
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Abstract

Erdheim–Chester disease is a rare form of nonLangerhans cell histiocytosis with multiorgan infiltration that occurs mainly in adults Pediatric cases are extremely rare Here we report a case of multisystemic Erdheim–Chester disease in a 15yearold boy with central nervous system involvement and skeletal findings Positron emission tomography PET and MRI were used to demonstrate characteristic bilateral symmetrical medullary involvement of the metadiaphyses of long bones in the absence of the classic sclerotic radiographic appearance This illustrates the potential for earlier diagnosis and visualization of therapeutic response in children

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