Authors: Andrew M Kropinski Melissa Hayward M Dorothy Agnew Ken F Jarrell
Publish Date: 2004/11/17
Volume: 9, Issue: 2, Pages: 99-109
Abstract
The sequence of the genome of the first alkaliphilic bacteriophage has been determined Temperate phage BCJA1 possesses a terminally redundant genome of approximately 41 kb with a mol G+C content of 417 and 59 genes arranged predominantly into two divergent transcriptons The integrase gene of this phage is unique in that it contains a ribosomal slippage site While this type of translational regulation occurs in the synthesis of transposase this is the first time that it has been observed in a bacteriophage integrase The DNA replication recombination packaging and morphogenesis proteins show their greatest sequence similarity to phages and prophages from the genus Streptococcus Host specificity lysin and lysogeny maintenance functions are most closely related to genes from Bacillus species
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