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Title of Journal: J Anesth

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Abbravation: Journal of Anesthesia

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Springer Japan

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DOI

10.1016/j.bbadis.2010.05.001

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1438-8359

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Sivelestat treatment for acute respiratory distres

Authors: Shigekiyo Matsumoto Seigou Hidaka Koji Goto Satoshi Hagiwara Chihiro Shingu Hideo Iwasaka Takayuki Noguchi
Publish Date: 2009/05/15
Volume: 23, Issue: 2, Pages: 288-291
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Abstract

Resuscitation and acute cerebral damage after cardiopulmonary arrest often induce a systemic inflammatory response and subsequently cause multiple organ failure including acute lung injury ALI Sivelestat has been reported to be effective for ALI associated with systemic inflammatory response syndrome SIRS but the effectiveness and safety of the drug for infants has not been confirmed We report a 33dayold infant who developed acute respiratory distress syndrome ARDS following hypoxic encephalopathy immediately after successful resuscitation from cardiopulmonary arrest Sivelestat was administered continuously for 7 days with no adverse reactions and consolidations on a chest radiograph were diminished and impaired oxygenation was markedly alleviated Our experience suggests that intravenous sivelestat offers a new therapeutic strategy for infantile ARDS/ALI but further investigation of the indication administration period and dosage is required

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Other Papers In This Journal:
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  2. The difficult airway with recommendations for management – Part 1 – Difficult tracheal intubation encountered in an unconscious/induced patient
  3. Comparing face-to-face intubation with different devices
  4. Frailty and perioperative outcomes: a narrative review
  5. Propofol infusion for sedation during spinal anesthesia
  6. Low-dose but not high-dose prostaglandin E 1 improves the histological outcome of severe forebrain ischemia in rats
  7. No evidence for superiority of air or oxygen for neonatal resuscitation: a meta-analysis
  8. Amino acid infusions started after development of intraoperative core hypothermia do not affect rewarming but reduce the incidence of postoperative shivering during major abdominal surgery: a randomized trial
  9. Sleep and Anesthesia: Neural Correlates in Theory and Experiment
  10. Management of blood pressure alters cerebral oxygen saturation values in the beach-chair position
  11. Comparison of the analgesic effect of intravenous acetaminophen with that of flurbiprofen axetil on post-breast surgery pain: a randomized controlled trial
  12. Awake postural change to prone in a morbidly obese patient
  13. Hospital administrative database underestimates delirium rate after cardiac surgery
  14. The effect of body mass index on the spread of spinal block in patients with rheumatoid arthritis
  15. Low-fidelity simulation improves mastery of the aseptic technique for labour epidurals: an observational study
  16. Time course of changes in cerebral blood flow velocity after tourniquet deflation in patients with diabetes mellitus or previous stroke under sevoflurane anesthesia
  17. The effects of 2-chloroprocaine on coagulation and fibrinolysis in the parturient: an in vitro study
  18. Calibration of the neuromuscular monitor: Is it necessary?
  19. In reply: Combined use of flexible bronchoscopy and video laryngoscopy for endotracheal intubation in patients with King laryngeal tube in situ
  20. The real cost of care: focus on value for money, rather than price-tags
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  37. Reducing Mortality in Critically Ill Patients
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  57. The effects of remifentanil or acetaminophen with epidural ropivacaine on body temperature during labor
  58. Continuous lumbar transversus abdominis plane block may spread to supraumbilical dermatomes
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  61. Effectiveness of preoperative screening for sickle cell disease in a population with a newborn screening program: a cohort study
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