Authors: Demet Coskun Hulya Celebi Gozde Karaca Lale Karabiyik
Publish Date: 2010/03/13
Volume: 24, Issue: 3, Pages: 373-379
Abstract
Forty consenting patients scheduled for elective septorhinoplasty were prospectively studied as one of two groups fentanyl group F or remifentanil group R After loading boluses of fentanyl 3 μg kg−1 or remifentanil 1 μg kg−1 were administered the continuous infusion of fentanyl or remifentanil was started at a rate of 003 or 015 μg kg−1 min−1 respectively Propofol infusion was then commenced with a 3 μg ml–1 effect site concentration Ce by means of a TCI device The Ce propofol was adjusted to keep BIS at 50 ± 10The general mean value of propofol Ce for group F and group R was 40 and 35 μg ml−1 respectively As to the recovery profile the eye opening time mean 67 vs 46 min extubation time mean 73 vs 47 min and orientation time mean 76 vs 49 min were found to be significantly longer in group F than in group RWe concluded that in propofolbased TCI anesthesia under BIS supervision for septorhinoplasty operations remifentanil was better than fentanyl especially with respect to emergence from total intravenous anesthesia TIVA Furthermore the durations of anesthesia and operation were rather short which indicates that fentanyl can be safely used
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