Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Infection

Search In Journal Title:

Abbravation: Infection

Search In Journal Abbravation:

Publisher

Urban & Vogel

Search In Publisher:

DOI

10.1007/s10643-012-0562-5

Search In DOI:

ISSN

1439-0973

Search In ISSN:
Search In Title Of Papers:

Increasing Occurrence of MultidrugResistance in

Authors: M Wadl K Heckenbach I Noll S Ziesing W Pfister J Beer S Schubert T Eckmanns
Publish Date: 2010/01/27
Volume: 38, Issue: 1, Pages: 47-51
PDF Link

Abstract

Acinetobacter baumannii can cause severeinfections mainly in critically ill inpatients Treatment iscomplicated by multidrugresistance MDR In Germany todate little is known on the extent of MDR in A baumanniiisolated from inpatients in German hospitals and potentialfactors influencing the emergence of MDRWe retrospectively analysed thedata of A baumannii isolates from the inpatients of fourGerman university hospitals tested for antimicrobial resistancewith the broth dilution method between 2002 and2006 We defined MDR as resistance to three or more classesof recommended drugs After calculating the proportions ofMDR in A baumannii isolates we investigated the associationbetween MDR in A baumannii and year of pathogenisolation hospital ward type specimen and demographicsWe performed descriptive analysis and multivariable logisticregression Additionally proportions of in vitro drug effectivenessagainst multidrugresistant and nonmultidrugresistantA baumannii isolates were determinedMDR was found in 66 of 1190 56A baumannii isolates and increased from 21 in 2002 to79 in 2006 The highest proportions of MDR were foundin hospital A 89 in intensive care units 73 inisolates from blood 76 and in male patients aged60 years or older 66 In multivariable analysis thechance of MDR in A baumannii isolates increased with thesuccessive years of pathogen isolation odds ratio OR 1395 confidence interval CI 11–15 and there was ahigher risk of MDR in A baumannii in intensive care unitsOR 18 95 CI 11–29 The lowest in vitro antibioticresistance was found in meropenem imipenem and ampicillin/sulbactam with 33 37 and 39 for multidrugresistantand 04 1 and 3 in nonmultidrugresistantA baumannii isolates respectivelyThe increase of MDR in A baumannii isolatesfrom 2002 to 2006 in four hospitals suggests that cliniciansin Germany may expect a rising proportion of MDR inA baumannii isolates among inpatients The antimicrobialsusceptibility testing of A baumannii isolates against recommendeddrugs combined with inhouse antimicrobial resistancesurveillance is needed to ensure appropriate treatment


Keywords:

References


.
Search In Abstract Of Papers:
Other Papers In This Journal:

  1. Malassezia Species: A Rare Cause of Invasive Fungal Infections in Immunocompromised Patients
  2. Evaluation of the NanoCHIP ® Infection Control Panel test for direct detection and screening of methicillin-resistant Staphylococcus aureus (MRSA), Klebsiella pneumoniae carbapenemase (KPC)-producing bacteria and vancomycin-resistant Enterococcus (VRE)
  3. Endocarditis caused by Streptococcus canis : an emerging zoonosis?
  4. Antineutrophil cytoplasmic antibody-associated vasculitis associated with Epstein–Barr virus infection: a case report and review of the literature
  5. Zur Diffusion von Cefotaxim in verschiedene Gewebe des urologischen Bereichs
  6. Validation of a multiplex reverse transcriptase PCR ELISA for the detection of 19 respiratory tract pathogens
  7. Interferon-γ releasing assay versus tuberculin skin testing for latent tuberculosis infection in targeted screening programs for high risk immigrants
  8. Complicated Community-Acquired Soft Tissue Infection by MRSA from Porcine Origin
  9. Human metapneumovirus infection after allogeneic hematopoietic stem cell transplantation
  10. Reasons for not starting antiretroviral therapy in HIV-1-infected individuals: a changing landscape
  11. Serum Citrate Levels, Haptoglobin Haplotypes and Transferrin Receptor (CD71) in Patients With HIV-1 Infection
  12. Immune-Mediated Severe Hemolytic Crisis with a Hemoglobin Level of 1.6 g/dl Caused by Anti-Piperacillin Antibodies in a Patient with Cystic Fibrosis
  13. Combination of Quinupristin/Dalfopristin and Glycopeptide in Severe Methicillin-Resistant Staphylococcal Infections Failing Previous Glycopeptide Regimens
  14. Challenging cases discussed by experts: retinal vasculitis following coinfection with HIV and syphilis
  15. Extended-spectrum β-lactamase-producing Escherichia coli strains in the feces of carriers contribute substantially to urinary tract infections in these patients
  16. Relevance of intracranial hypertension control in the management of Cryptococcus neoformans meningitis related to AIDS
  17. A case of postmalaria neurological syndrome in Japan
  18. Produktion und Reinigung des thermolabilen Escherichia coli-Enterotoxins
  19. Economic burden of Clostridium difficile associated diarrhoea: a cost-of-illness study from a German tertiary care hospital
  20. Current Antifungal Agents for Treatment of Central Nervous System Infections
  21. Experience with daptomycin daily dosing in ICU patients undergoing continuous renal replacement therapy
  22. Failure of Current Antibiotic First-Line Regimens and Mortality in Hospitalized Patients with Spontaneous Bacterial Peritonitis
  23. Das Buckley-Syndrom: Rezidivierende, schwere Staphylokokken-infektionen, Ekzem und Hyperimmunglobulinämie E
  24. Diagnosis of prosthetic joint infections using UMD-Universal Kit and the automated multiplex-PCR Unyvero i60 ITI ® cartridge system: a pilot study
  25. Why is antimicrobial de-escalation under-prescribed for urinary tract infections?
  26. Is aciclovir prophylaxis necessary after bone marrow transplantation?
  27. Rare Fungal Infections in Children: An Updated Review of the Literature
  28. Combination antibiotic therapy for the treatment of infective endocarditis due to enterococci
  29. Diagnosis of tubercular uveitis by quantitative polymerase chain reaction
  30. New developments in the antifungal susceptibility testing of Candida
  31. The in vitro activity of ampicillin, amoxicillin, cephalexin, nitrofurantoin, sulphadiazine and trimethoprim against Streptococcus agalactiae isolated from urinary and other infections
  32. Reply: Is it really Aeromonas hydrophila ?
  33. Comparison of the clinical characteristics of Mycobacterium tuberculosis and nontuberculous mycobacteria patients with joint involvement
  34. Detection of Early Liver Fibrosis in Patients with Intestinal Schistosomiasis: Sonographic and Histologic Findings in Schistosoma mansoni Infection
  35. Hepatitis E virus in the countries of the Middle East and North Africa region: an awareness of an infectious threat to blood safety
  36. Asepsis und Antisepsis bei der Behandlung des Brandverletzten
  37. Bloodstream infection due to extended-spectrum beta-lactamase (ESBL)-positive K. pneumoniae and E. coli : an analysis of the disease burden in a large cohort
  38. Intrathecal/intraventricular colistin in external ventricular device-related infections by multi-drug resistant Gram negative bacteria: case reports and review

Search Result: