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Title of Journal: J GEN INTERN MED

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Abbravation: Journal of General Internal Medicine

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Springer-Verlag

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10.1016/0022-328x(92)83041-f

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1525-1497

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Concurrent Sweet’s Syndrome and Erythema Nodosum

Authors: Tracie Harris Mark C Henderson
Publish Date: 2010/10/16
Volume: 26, Issue: 2, Pages: 214-215
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Abstract

Erythema nodosum EN is a form of panniculitis characterized by painful red nodules over the pretibial area Sweet’s syndrome SS is an acute febrile neutrophilic dermatosis characterized by fever leukocytosis and erythematous plaques involving the arms trunk and neck Vesiculopustules nodules and ulcers may also occur Simultaneous occurrence of EN and SS has been increasingly reported and both appear to be reactive dermatoses with overlapping clinical and histopathologic features Although often idiopathic both disorders have been associated with upper respiratory infections medications hematologic malignancies and autoimmune disease eg rheumatoid arthritis and inflammatory bowel disease Treatment includes corticosteroids potassium iodide or colchicine SS generally responds well to therapy but recurs in up to 25 of patients 15 have a chronic relapsing courseExtensive evaluation was unrevealing including chest and abdominal imaging bone marrow biopsy endoscopy and serologies for hepatitis syphilis recent Streptococcal infection and rheumatologic disorders He responded well to oral prednisone The underlying cause was presumed to be an antecedent upper respiratory tract infectionThis article is published under an open access license Please check the Copyright Information section for details of this license and what reuse is permitted If your intended use exceeds what is permitted by the license or if you are unable to locate the licence and reuse information please contact the Rights and Permissions team

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