Authors: Mona Siddiqui Michael T Melia
Publish Date: 2014/04/15
Volume: 29, Issue: 9, Pages: 1308-1308
Abstract
There are many different diseases associated with clubbing Pulmonary diseases are most commonly associated but cardiac conditions gastrointestinal diseases and various infections are also found with clubbing The patient’s evaluation included unremarkable labs for systemic diseases such as malignancy liver disease and inflammatory bowel disease His cardiopulmonary evaluation included echocardiography pulmonary function testing polysomnography and chest computed tomography These were also unrevealing The patient’s PPD test and RPR were nonreactive His HIV antibody test with Western blot returned positive CD4+ lymphocyte count was 401/μL and viral load was 205000 copies/mL1Digital clubbing is associated with HIV Among one convenience sample of 76 HIVinfected patients 28 36 had objectively confirmed clubbing—thus HIV testing is recommended as part of a diagnostic algorithm12 While HIV screening is now recommended for all patients aged 15–65 years this case highlights the need for HIV diagnostic testing in patients with digital clubbing3
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