Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Sci China Life Sci

Search In Journal Title:

Abbravation: Science China Life Sciences

Search In Journal Abbravation:

Publisher

Science China Press

Search In Publisher:

DOI

10.1007/s10956-016-9611-y

Search In DOI:

ISSN

1869-1889

Search In ISSN:
Search In Title Of Papers:

Isolation and differentiation of neural stem/proge

Authors: Yun Gu Nan Hu Jie Liu Fei Ding XiaoSong Gu
Publish Date: 2010/11/23
Volume: 53, Issue: 9, Pages: 1057-1064
PDF Link

Abstract

To find a promising alternative to neurons or schwann cells SCs for peripheral nerve repair applications this study sought to isolate stem cells from fetal rat dorsal root ganglion DRG explants Molecular expression analysis confirmed neural stem cell characteristics of DRGderived neurospheres in terms of expressing neural stem cellspecific genes and a set of welldefined genes related to stem cell niches and glial fate decision Under the influence of neurotrophic factors bFGF and NGF the neurospheres gave rise to neurofilamentexpressing neurons and S100expressing Schwann celllike cells by different pathways This study suggests that a subpopulation of stem cells that reside in DRGs is the progenitor of neurons and glia which could directly induce the differentiation toward neurons or SCs

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. Identification of genes contributing to quantitative disease resistance in rice
  2. Localization and characterization of the hypothetical protein CT440 in Chlamydia trachomatis -infected cells
  3. Single-base resolution analysis of DNA epigenome via high-throughput sequencing
  4. Determinants of uterine aging: lessons from rodent models
  5. Suppression of glutamate synthase genes significantly affects carbon and nitrogen metabolism in rice ( Oryza sativa L.)
  6. Spontaneous high-frequency action potential
  7. T2 relaxation time measurements in the brains of scalded rats
  8. Delivering noninvasive prenatal testing in a clinical setting using semiconductor sequencing platform
  9. What does H7N9 mean and how can we be prepared for the next flu pandemic?
  10. A bacterial artificial chromosome transgenic mouse model for visualization of neurite growth
  11. CFTR: a missing link between exocrine and endocrine pancreas?
  12. A single mutation in the P BC loop of VP2 is involved in the in vitro replication of infectious bursal disease virus
  13. Molecular mechanisms of dietary restriction in aging—insights from Caenorhabditis elegans research
  14. Regulation of innate receptor pathways by microRNAs
  15. Dynamic microenvironment and multiple damaged tissue regeneration in a de novo and synchronized manner
  16. Engineering imaging probes and molecular machines for nanomedicine
  17. Mineralocorticoid receptor: a critical player in vascular remodeling
  18. How the coevolution of language and sociality has helped to shape the human brain
  19. The Yin and Yang of Wnt/Ryk axon guidance in development and regeneration
Search Result: