Authors: Heather A Jacene Christian C Cohade Zhe Zhang Richard L Wahl
Publish Date: 2010/12/08
Volume: 13, Issue: 6, Pages: 1278-1283
Abstract
Nine hundred eight patients had PET/CT scans and were previously identified as having or not having FDG uptake in BAT The original database was retrospectively reviewed for blood glucose level and body mass index BMI at the time of imaging Blood glucose levels were compared between patients with or without FDG uptake in BAT adjusting for age sex and BMIFiftysix patients 62 had FDG uptake in BAT In the univariate analysis patients without FDG uptake in BAT had a higher risk of glucose ≥100 mg/dL odds ratio 34 95 CI = 1673 P = 00007 After adjustment for age sex BMI and significant interaction of sex and BMI patients without BAT tended to have a higher risk of glucose ≥100 mg/dL although not statistically significant odds ratio = 16 95 CI = 0736 P = 0268Although causal relationships are not specified the data suggest that BAT uptake glucose levels BMI sex and age are interrelated and the possibility that presence of “detectable” BAT is protective against diabetes and obesity FDG PET/CT may be a vital tool for further investigations of diabetes and obesity
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