Authors: Ronen Bar Kinga Przewloka Rachel Karry Alex Frenkel Avishay Golz Zohar Keidar
Publish Date: 2011/12/14
Volume: 14, Issue: 5, Pages: 647-651
Abstract
Reduced SPECT acquisition time protocols have been recently developed based on collimatordetector response compensation reconstruction The present study aims to evaluate the potential use of a shorttime technetium99m methoxyisobutylisonitrile Tc99mMIBI SPECT algorithm in the investigation of parathyroid adenoma PTANinety patients 59 women age range 21–76 years with biochemical evidence of hyperparathyroidism were referred for Tc99mMIBI scintigraphy for diagnosis and localization of PTA Standard fulltime and halftime SPECT studies starting at 45 min after injection were performed in random order in all patients PTA detection rate and overall image quality parameters were evaluated and graded for each study and compared for the two SPECT protocolsFocal 99mTcsestamibi uptake consistent with PTA was reported in 60 out of 90 studies 67 Congruent results between the full and halftime SPECT acquisition were found in 73 patients 81 Minor disagreement between the two SPECT protocols with respect to PTA detectability was found in 17 patients but with no statistically significant difference p = 067 The correlation coefficient between the two SPECTs was r = 088 p 00001 and the Bland–Altman correlation analysis confirmed the interchangeability of the two protocols Image quality was reported as either good or excellent for all studies and no statistical significant difference in image quality scoring between protocols was found p = 0155
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