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Title of Journal: Mol Imaging Biol

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Abbravation: Molecular Imaging and Biology

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Springer-Verlag

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DOI

10.1007/pl00020545

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1860-2002

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Dynamic Changes of FDG Uptake and Clearance in Nor

Authors: Gang Cheng Abass Alavi Esther Lim Thomas J Werner Catherine V Del Bello Scott R Akers
Publish Date: 2012/10/23
Volume: 15, Issue: 3, Pages: 345-352
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Abstract

The aorta blood pool liver and spleen FDG activity demonstrated significantly and continuously decreased activity from 1 to 2 and 2 to 3 h while FDG uptake in the lungs pancreas lymph nodes and skeletal muscle decreased from 1 to 2 h only In contrast the left ventricular myocardium demonstrated two patterns of dynamic changes myocardium with higher FDG uptake SUVmax ≥ 325 on the initial images had more remarkable increased activity on the delayed images while myocardium with lower FDG uptake SUVmax  325 on the initial imaging had no increased uptake on delayed imaging Increased FDG uptake was also observed in the bones on the delayed images No significant changes of FDG uptake were noted in the parotid gland thyroid gland and prostate glandThese findings may help nuclear medicine physicians when comparing images performed at different time points when using FDG uptake in internal reference regions as a relative indicator of FDG uptake in a specific lesion and when reading a delayed FDG PET imaging


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