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Title of Journal: Jpn J Ophthalmol

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Abbravation: Japanese Journal of Ophthalmology

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Springer Japan

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DOI

10.1007/bf00223482

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1613-2246

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Validation of international criteria for the diagn

Authors: Hiroshi Takase Kentarou Shimizu Yukiko Yamada Atsue Hanada Hidemi Takahashi Manabu Mochizuki
Publish Date: 2011/01/28
Volume: 54, Issue: 6, Pages: 529-536
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Abstract

A retrospective casecontrol study examined 370 consecutive uveitis patients at Tokyo Medical and Dental University Hospital The study group consisted of 50 patients with biopsyproven sarcoidosis and 320 control patients with other uveitis entities Predictive values sensitivity specificity positive predictive value PPV and negative predictive value NPV were calculated for seven clinical signs five laboratory tests and the diagnostic criteriaWith the exception of the liver enzyme tests there was a significantly higher incidence of positive results for all clinical signs and laboratory tests in the biopsyproven sarcoidosis patients than in the control uveitis patients Although variability was noted in the predictive values of the seven clinical signs and five laboratory tests the sensitivity specificity PPV and NPV of the FIWOS criteria which were based on the combined results of the clinical signs and laboratory tests were 1000 0956 0781 and 1000 respectively

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