Authors: Yuichi Uchino Miki Uchino Murat Dogru Samantha Ward Norihiko Yokoi Kazuo Tsubota
Publish Date: 2011/11/15
Volume: 56, Issue: 1, Pages: 8-13
Abstract
We recruited 295 individuals 81 men 214 women average age 436 ± 143 years seen for general ophthalmic checkup and dry eye examinations Using results of the Schirmer I test tear breakup time and fluorescein and Rose Bengal staining patients were diagnosed as having definite dry eye DDE probable dry eye PDE or as being normal according to both the old and new Japanese dry eye diagnostic criteriaMean ages of normal participants and patients with PDE and DDE were 370 ± 104 417 ± 144 and 477 ± 153 years respectively p 0001 All 37 individuals diagnosed as normal following the old criteria were also diagnosed as normal with the new diagnostic criteria Among the 60 patients diagnosed as PDE with the old criteria 19 317 were diagnosed as normal and 41 683 as PDE with the new diagnostic criteria Of the 198 patients diagnosed with DDE following the old criteria 59 297 were diagnosed as PDE and 139 702 as DDE with the new diagnostic criteria There was no significant difference in dry eye severity index scores between the old and new diagnostic criteriaA shift in the final dry eye diagnostic status from DDE to PDE and from PDE to normal was observed with the implementation of the new dry eye diagnostic criteria suggesting that patients at the severe end of the dry eye disease spectrum are now diagnosed as DDE disease under the new criteria
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