Authors: Noboru Inamura Akio Kubota Ryo Ishii Yoichiro Ishii Yukiko Kawazu Yuji Hamamichi Akihiro Yoneda Hisayuki Kawahara Hiroomi Okuyama Futoshi Kayatani
Publish Date: 2014/08/09
Volume: 30, Issue: 9, Pages: 889-894
Abstract
We treated 61 cases of ADCDH according to our strategy Prostaglandin E1 was required to be maintained the patency of the ductus arteriosus PDA in 39 cases Group I while it was not administered in 22 cases Group II Left ventricular enddiastolic dimension LVDD and Tei index were measured with echocardiography on days 0 2 and 7 after birth Radical surgery was performed on all cases by day 2On day 0 Group I showed smaller LVDD and Tei index than those in Group II Between day 0 and day 2 these parameters increased significantly in Group I but not in Group II On day 7 no significant difference in these parameters was observed between the two groups Five patients died of cardiac and respiratory failure resulting in a survival rate of 92 Our therapeutic strategy improves the clinical outcome of ADCDH This can be attributed to two factors earlier surgery resulting in improved LV function The latter attenuates pulmonary hypertension and maintains PDA with a consequent decrease in right ventricular afterload to compensate for the low cardiac output resulting from PDA
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