Authors: Helmut A Greim
Publish Date: 2008/11/26
Volume: 83, Issue: 1, Pages: 5-7
Abstract
During the next few years two major decisions of the European Commission will have great consequences for the use of animals to evaluate the adverse effects of chemicals on human health and the environment The first is the implementation of REACH It requests safety assessment of a large number of chemicals which according to the legislation should be based preferentially on alternatives to animal testing The second is the phasing out date for studies in animals March 2013 of the 7th amendment of the Cosmetics Guideline 76/768/EEC for repeated dose toxicity reproductive toxicity and carcinogenicityIn contrast to these expectations or even regulations Lilienblum et al 2008 recently concluded that both a significant reduction of animal testing for REACH and the phasing out of in vivo testing for cosmetics in a few years appear unrealistic Consequently the authors recommended that established in vivo tests at least at present should be considered indispensable as basic
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