Authors: Marzia Pettinicchio Tonino Traini Giovanna Murmura Sergio Caputi Marco Degidi Carlo Mangano Adriano Piattelli
Publish Date: 2010/11/03
Volume: 16, Issue: 1, Pages: 45-53
Abstract
The aim of this study was to compare the histological behavior of three bone graft materials placed in human The comparison was made among BioOss® BO Engipore® EP and PepGen P15® P15 Five biopsies for each group of biomaterial retrieved 6 months after sinus lift augmentation were analyzed The investigation was carried out using light microscope LM scanning electron microscope SEM with an energy dispersive spectrometer EDS and circularly polarized light microscope CPLM Under LM the amount of newly formed bone was significantly higher in BO than P15 P 05 while the amount of residual graft material was significantly higher in P15 than BO P 05 The extension of marrow spaces was significantly higher in EP than both BO and P15 P 05 SEMEDS analysis showed a Ca/P ratio of 18 for BO 22 for EP and 15 for P15 Under CPLM BO showed no significant difference for transverse 184 ± 27 and longitudinal 163 ± 18 bone collagen fibers P = 195 EP showed a significant difference between transverse 4 ± 07 and longitudinal 76 ± 25 bone collagen fibers P = 015 finally P15 showed no significant difference for transverse 38 ± 16 and longitudinal 49 ± 12 bone collagen fibers P = 279 No investigated biomaterial was completely resorbed but all the residual particles demonstrated a close bone integration to form a hybrid tissue BO particles appeared perfectly osseointegrated in the trabecular bone EP showed a tendency to concentrate the bone apposition into the microporosities P15 particles appeared bridged by newly formed bone trabeculae
Keywords: