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Title of Journal: Clin Oral Invest

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Abbravation: Clinical Oral Investigations

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Springer Berlin Heidelberg

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DOI

10.1007/bf02350275

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ISSN

1436-3771

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Shortterm changes on Creactive protein CRP lev

Authors: André Barbisan de Souza Rogério T P Okawa Cléverson O Silva Maurício G Araújo
Publish Date: 2016/04/12
Volume: 21, Issue: 1, Pages: 477-484
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Abstract

Twentytwo patients with chronic periodontitis test group and 22 periodontally healthy individuals control group both groups without any systemic disorder or potential confounding factors were included in the study At baseline periodontal clinical variables and CRP levels were obtained in both groups In the test group oral hygiene instruction and scaling and root planning were carried out then after 60 days periodontal clinical variables and CRP levels were reevaluatedThe baseline CRP level in the test group was significantly higher than the corresponding value in the control group 198 ± 155 vs 126 ± 105 mg/L p  005 After periodontal treatment in the test group there were improvements in all periodontal clinical variables p  005 The CRP level decreased significantly in those patients with higher baseline levels of CRP 3 mg/LThe authors thank the Biostatistician Alfa I Yansane PhD from the Oral Health Policy and Epidemiology Department–Harvard School of Dental Medicine for the supervision on the statistical analyses and also Mr Antonio C Correa for the meticulous overall manuscript revisionAll procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards The study protocol was submitted reviewed and approved by the local ethical committee of the State University of Maringá 241/2009


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