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Title of Journal: Clin Oral Invest

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Abbravation: Clinical Oral Investigations

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Springer Berlin Heidelberg

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DOI

10.1016/0010-440x(83)90083-4

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1436-3771

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Increased immunoexpression of trefoil factors in s

Authors: Ponlatham Chaiyarit Poramaporn Klanrit Pensri Photipakdee Ajiravudh Subarnbhesaj Andrew S Giraud
Publish Date: 2013/08/20
Volume: 18, Issue: 4, Pages: 1305-1312
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Abstract

Very little is known about the role of trefoil factors TFFs in salivary gland tumors and TFF immunoexpression has never been investigated in such tumors The aim of this study was to evaluate TFF immunoexpression in benign and malignant salivary gland tumorsBenign n = 25 and malignant n = 25 salivary gland tumor specimens were included in this study using mucocele n = 25 specimens as a control group Immunohistochemical staining was performed to evaluate the expression of TFFs TFF1 TFF2 and TFF3 by semiquantitative meansExpression of TFF1 TFF2 and TFF3 was significantly increased in benign p = 0001 p = 0005 p  0001 respectively and malignant p  0001 p  0001 p  0001 respectively groups as compared with the control group Patterns of coexpression between TFF1/TFF2 TFF2/TFF3 and TFF1/TFF3 were different among the three groups

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