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Title of Journal: J Gastrointest Surg

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Abbravation: Journal of Gastrointestinal Surgery

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Springer-Verlag

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DOI

10.1007/s00405-011-1672-1

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1873-4626

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Clinicopathological Characteristics and Outcome of

Authors: QiBo Wang BoKang Cui JianMing Weng QiuLiang Wu JiLiang Qiu XiaoJun Lin
Publish Date: 2012/07/06
Volume: 16, Issue: 9, Pages: 1715-1726
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Abstract

In the SC group six patients had hepatocellular carcinoma and four had cholangiocellular carcinoma while in the CS group it was nine and five patients respectively All cases of the sarcomatous components were vimentinpositive Pancytokeratin were stained in sarcomatous components of the SC group but not in the CS group The sarcomatous component in the SC group was negative for desmin myoglobin HHF35 SMA CD68 Mac387 AAT CD34 and S100 In the CS group the sarcomatous components in six cases were malignant fibrous histiocytomas six were fibrosarcomas and two were rhabdomyosarcomas Median survival times were 96 and 48 months for the SC and CS groups respectively P = 0483 In univariate analysis favorable predictors of overall survival were asymptomatic Child–Pugh class A no distant metastasis and radical resectionSC and CS were highly aggressive malignancies with similar poor survival regardless of the histological and immunohistochemical findings Early detection through regular physical examination and treatment with radical resection may improve the outcome of those patients

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