Authors: Keith M Cavaness M B Majella Doyle Yiing Lin Erin Maynard William C Chapman
Publish Date: 2012/09/21
Volume: 17, Issue: 1, Pages: 207-212
Abstract
Large or critically located hepatic tumors continue to be a challenge for surgeons as they push to obtain adequate surgical margins and often leave less residual liver behind While it has been shown that up to 80 of a healthy liver can be resected additional challenges exist with the “less than healthy liver” when planning an operative procedure and determining the future liver remnant FLR volume The main goal is to obtain adequate margins while avoiding postoperative liver decompensation and failure Postoperative liver failure PLF has been reported to have a mortality rate as high as 32 and is often associated with sepsis and multisystem organ failure1It has been shown that patients without liver disease normal background liver can recover with an FLR volume of greater than or equal to 25 without significant postoperative sequelae2However as we progress down the pathway of liver dysfunction patients with chronic liver disease but without cirrhosis
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