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Title of Journal: J Gastrointest Surg

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Abbravation: Journal of Gastrointestinal Surgery

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Springer US

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10.1016/j.actamat.2014.01.056

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1873-4626

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Sphincter of Oddi Dysfunction How Is It Diagnosed

Authors: Attila Nakeeb
Publish Date: 2013/07/17
Volume: 17, Issue: 9, Pages: 1557-1558
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Abstract

Sphincter of Oddi dysfunction SOD refers to an abnormal contractility of the sphincter of Oddi resulting in impedance to the flow of bile and pancreatic juice thru the ampulla of Vater Under normal circumstances the sphincter of Oddi is responsible for regulating pressures in the pancreaticobiliary tree determines the direction and rate of bile and pancreatic juice flow into the duodenum and diverts bile into the gallbladder It is also responsible for preventing duodenal reflux into the liver and the pancreasSphincter of Oddi dysfunction is a benign noncalculous obstructive disorder occurring at the level of the sphincter of Oddi which causes pancreaticobiliarytype pain Patients may present with cholestasis and/or pancreatitis The etiology of SOD may be from either an anatomic stricture at the ampulla of Vater from the passage of a gallstone or may be a functional abnormality due to a congenital hypertrophic sphincter or a hypertensive sphincter that is hyperresponsive to

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