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Title of Journal: Pediatr Cardiol

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Abbravation: Pediatric Cardiology

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Springer-Verlag

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DOI

10.1016/0264-9993(95)00027-5

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1432-1971

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Increased Incidence of Incomplete Kawasaki Disease

Authors: Sunil J Ghelani Craig Sable Bernhard L Wiedermann Christopher F Spurney
Publish Date: 2012/02/15
Volume: 33, Issue: 7, Pages: 1097-1103
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Abstract

We sought to study the impact of the 2004 American Heart Association guidelines on diagnosis and treatment of patients with Kawasaki disease KD We reviewed patient records from July 2000 to June 2002 group 1 and July 2007 to June 2009 group 2 at a tertiary children’s hospital The proportion of patients with incomplete KD in group 2 56 of 118 47 was significantly higher than that in group 1 20 of 85 24 p = 0001 Median age months and interquartile ranges for group 1 was 26 range 125–52 and for group 2 was 385 range 18–63 p = 0072 The number of patients diagnosed with KD having just 2 symptoms other than fever was significantly higher in group 2 24 vs 169 p  0001 Erythrocyte sedimentation rate albumin and alanine aminotransferase levels were obtained in a significantly greater number of patients with KD after the guidelines were published Thirtytwo of the 203 patients studied had coronary artery CA involvement 158 4 of whom had CA aneurysms 2 and 28 had CA ectasia only 138 CA involvement was seen in 13 of 85 153 patients in group 1 and 19 of 118 161 p = 1 patients in group 2 After publication of the 2004 AHA guidelines diagnoses of incomplete KD and laboratory use increased at our center however the rate of CA involvement remained stable There also was a trend towards older age in children diagnosed with KD Laboratory parameters and CA involvement between incomplete KD and classic KD were comparable

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