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Title of Journal: Bull Mater Sci

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Abbravation: Bulletin of Materials Science

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Springer India

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DOI

10.1007/bf00901235

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0973-7669

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Influence of mineral phase in mineralization of a

Authors: Krithiga Gunasekaran Santhosh Kumar Baskar Divya Sapphire Mohan Thotapalli P Sastry
Publish Date: 2014/06/10
Volume: 37, Issue: 3, Pages: 729-733
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Abstract

A resorbable composite which acts as a active barrier in guided bone regeneration was fabricated using chitosan demineralized bone matrix and bone ash Its potential to form bone like apatite in simulated body fluid was assessed in this study The mechanical strength of these composites was correlated with bone ash ratios and composites with better tensile strength were studied for their acellular bioactivity by incubating in simulated body fluid for 21 days Composites without bone ash did not show acellular bioactivity which was confirmed by thermogravimetric analysis In case of biocomposites with bone ash there was an increase in residual weight indicating the mineralization of the composite The composite containing bone ash has shown the peaks related to phosphate vibrations in its Fouriertransform infrared spectrum Scanning micrographs revealed formation of apatite like crystals on its surface Ca/P ratio was found to be 1·7 which is nearer to that of natural bone Thus prepared composites can be used as resorbable biocomposite in maxillofacial and oral defects

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