Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Pathol Oncol Res

Search In Journal Title:

Abbravation: Pathology & Oncology Research

Search In Journal Abbravation:

Publisher

Springer Netherlands

Search In Publisher:

DOI

10.1002/ange.201402315

Search In DOI:

ISSN

1532-2807

Search In ISSN:
Search In Title Of Papers:

Phenotypical Characteristics of the Immune Cells i

Authors: Mahmoud Rezk A Hussein Wafaa M AbdelMagid Ramadan Saleh Essam Nada
Publish Date: 2008/09/17
Volume: 15, Issue: 1, Pages: 73-79
PDF Link

Abstract

Allergic contact dermatitis ACD is a cellmediated delayed type IV immunologic reaction Atopic dermatitis AD is a chronic inflammatory skin disease that results from a complex interaction between immunologic genetic and environmental factors Pityriasis rosea PR is a selflimited eruption of unknown etiology Immune cell infiltrate is a constant feature in the inflammatory skin diseases Here we performed phenotypical characterization of the immune cells in ACD AD and PR ten cases each We performed immunohistochemical stains for B cells CD20 T cells CD3 histiocytes CD68 and T cells with cytotoxic activity granzymeB The data were compared with findings in 20 specimens of normal skin The results were scored as mean values of positively stained immune cells Immunohistochemistry showed significantly high counts of immune cells in lesional skin ACD AD and PR compared to the normal one p  005 In the lesional skin the immune cells were composed predominantly of CD3+ T lymphocytes and CD68+ cells histiocytes Some of the CD3+ cells were granzyme B+ The counts of some immune cells CD3+ and CD68+ were high in ACD compared to AD and PR The counts of CD20+ and granzyme B+ cells were high in PR compared to ACD and AD However these differences did not reach the level of statistical significance The present data describe the profile of the immune cell infiltrate in AD ACD and PR The cellmediated immunity seems to have critical role in the development of these lesions

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. Clinico-Pathological Particularities of the Shock-Related Pancreatitis
  2. Lymphoproliferative Disorders After Solid Organ Transplantation—Classification, Incidence, Risk Factors, Early Detection and Treatment Options
  3. Tumor Grade versus Expression of Invasion-Related Molecules in Astrocytoma
  4. Primary Adamantinoma of the Rib. Unusual Presentation for a Bone Neoplasm of Uncertain Origin
  5. Neuroendocrine Tumors of Extrahepatic Biliary Tract
  6. Frameshift Mutations of SMG7 Essential for Nonsense-Mediated mRNA Decay in Gastric and Colorectal Cancers
  7. K-ras Mutation, HPV Infection and Smoking or Alcohol Abuse Positively Correlate with Esophageal Squamous Carcinoma
  8. Claudin-1 as a Biomarker of Cervical Cytology and Histology
  9. Adult Extrarenal Wilms’ Tumor Mimicking Mixed Epithelial and Stromal Tumor in the Retroperitoneum: A Case Report with Immunohistochemical Study and Review of the Literature
  10. Entire-volume Serial Histological Examination for Detection of Micrometastases in Lymph Nodes of Colorectal Cancers
  11. Expression of TGFβ1 and Its Signaling Components by Peripheral Lymphocytes in Systemic Lupus Erythematosus
  12. Diagnostic Concordance in Reporting Breast Needle Core Biopsies using the B Classification—A Panel in Italy
  13. Expression and Clinical Significance of FAK and Src Proteins in Human Endometrial Adenocarcinoma
  14. Subcutaneous Calcification as a Delayed Complication of Radiotherapy: A Case Report and Review of the Literature
  15. Expression of Matrilin-2 in Liver Cirrhosis and Hepatocellular Carcinoma
  16. Reversing Multidrug-Resistant by RNA Interference Through Silencing MDR1 Gene in Human Hepatocellular Carcinoma Cells Subline Bel-7402/ADM
  17. Genetic Polymorphism of XRCC1 Correlated with Response to Oxaliplatin-Based Chemotherapy in Advanced Colorectal Cancer
  18. Polymorphism of UBC9 Gene Encoding the SUMO-E2-Conjugating Enzyme and Breast Cancer Risk
  19. Variations in EGFR ctDNA Correlates to the Clinical Efficacy of Afatinib in Non Small Cell Lung Cancer with Acquired Resistance
  20. Meta-Analysis for the Therapeutic Effect of Neoadjuvant Therapy in Resectable Esophageal Cancer
  21. Tumor Preventive Efficacy of Emodin in 7,12-Dimethylbenz[a]Anthracene-Induced Oral Carcinogenesis: a Histopathological and Biochemical Approach
  22. Serum Vascular Endothelial Growth Factors A, C and D in Human Breast Tumors
  23. 4-1BB Protects Dendritic Cells from Prostate Cancer-Induced Apoptosis
  24. Biologic Evaluation of Diabetes and Local Recurrence in Non-Small Cell Lung Cancer
  25. The Expression of High Mobility Group Box 1 is Associated with Lymph Node Metastasis and Poor Prognosis in Esophageal Squamous Cell Carcinoma
  26. Autologous Dendritic Cell Based Adoptive Immunotherapy of Patients with Colorectal Cancer—A Phase I-II Study
Search Result: