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Title of Journal: Int J Legal Med

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Abbravation: International Journal of Legal Medicine

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Springer-Verlag

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DOI

10.1007/s12652-010-0033-z

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1437-1596

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Seventeen Ychromosomal short tandem repeat haplot

Authors: HsiaoLin Hwa LiHui Tseng TsangMing Ko YihYuan Chang HsiangYi Yin YiNing Su James ChunI Lee
Publish Date: 2010/02/24
Volume: 124, Issue: 4, Pages: 295-300
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Abstract

The analysis of Ychromosome short tandem repeat YSTR loci is a powerful tool in forensic casework The aim of this study was to present the 17 YSTR loci haplotype distributions of groups of population living in Taiwan and to demonstrate genetic distances between the groups as well as multidimensional scaling plot based on YSTR genotype data Five hundred and fifteen DNA samples from unrelated males of seven groups of population including Taiwanese Han two groups of indigenous Taiwanese of Taiwan Island Tao mainland Chinese Filipinos and a group of people with European Near Eastern or South Asian ancestry were analyzed using a commercial kit that coamplifies 17 YSTRs A total of 471 different haplotypes with 440 unique haplotypes were identified The overall haplotype diversity was 09995 ± 00002 High haplotype diversity was observed in six groups of population except the Tao These YSTRs revealed a low discrimination capacity in the Tao population 3684 which should be considered in forensic practice The multidimensional scaling plot of these seven groups of population constructed based on the genetic distances according to 17 YSTR loci presented a clear patrilineal genetic substructure in the area Partial YSTRs profiling reduced the discrimination capacity in most groups of population and distorted the multidimensional scaling plot

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