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Title of Journal: Int J Legal Med

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Abbravation: International Journal of Legal Medicine

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Springer Berlin Heidelberg

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DOI

10.1007/s12275-008-0097-z

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1437-1596

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Postmortem magnetic resonance imaging of the heart

Authors: C Bruguier C Egger J P Vallée J Grimm X Boulanger C Jackowski P Mangin S Grabherr
Publish Date: 2014/08/10
Volume: 129, Issue: 3, Pages: 559-567
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Abstract

Postmortem MRI PMMR examinations are seldom performed in legal medicine due to long examination times unfamiliarity with the technique and high costs Furthermore it is difficult to obtain access to an MRI device used for patients in clinical settings to image an entire human body An alternative is available ex situ organ examination To our knowledge there is no standardized protocol that includes ex situ organ preparation and scanning parameters for postmortem MRI Thus our objective was to develop a standard procedure for ex situ heart PMMR examinations We also tested the oily contrast agent Angiofil® commonly used for PMCT angiography for its applicability in MRI We worked with a 3 Tesla MRI device and 32channel head coils Twelve porcine hearts were used to test different materials to find the best way to prepare and place organs in the device and to test scanning parameters For coronary MR angiography we tested different mixtures of Angiofil® and different injection materials In a second step 17 human hearts were examined to test the procedure and its applicability to human organs We established two standardized protocols one for preparation of the heart and another for scanning parameters based on experience in clinical practice The established protocols enabled a standardized technical procedure with comparable radiological images allowing for easy radiological reading The performance of coronary MR angiography enabled detailed coronary assessment and revealed the utility of Angiofil® as a contrast agent for PMMR Our simple reproducible method for performing heart examinations ex situ yields high quality images and visualization of the coronary arteriesThe authors thank Mr Pascal Chèvre radiographer deputy chief of the MRI unit of the Service of Diagnostic and Interventional Radiology form the University Hospital Lausanne and Bruno Bonet radiographer in the Brain Behaviour Laboratory of the University of Geneva for their appreciated help

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