Authors: Shiyan Yan Chen Yao Xiaorong Ding Miao Jiang Aiping Lu
Publish Date: 2011/12/03
Volume: 17, Issue: 12, Pages: 903-907
Abstract
To explore the effectiveness related indicators which might help identify the indications of Tongxinluo Capsule 通心络胶囊 and Kangxin Capsule 康欣胶囊 targeting on qi deficiency and blood stasis pattern in Chinese medicine CM in the treatment of angina pectorisThe data from a multicenter randomized and doubleblinded study conducted at 5 centers in China were obtained for the analysis A total of 239 patients with angina pectoris and CM syndrome of qi deficiency and blood stasis were randomly assigned in a 11 ratio to Tongxinluo Capsule group 119 cases and Kangxin Capsule group 120 cases Angina effectiveness and electrocardiogram ECG improvement were selected as the therapeutic outcomesAfter a 4week treatment the effective rates of Tongxinluo Capsule and Kangxin Capsule were 4370 and 2500 respectively P 005 Serum lowdensity lipoprotein LDL level was found to influence the effectiveness of Tongxinluo Capsule which had higher effective rate in the patients with lower level of LDL Heart rate was found to influence the effectiveness in the patients treated with Kangxin Capsule which had higher effective rate in the patients with heart rate ⩽80 beats/min
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