Authors: Xiaojuan Wang Jiansheng Guo Yin Xu Xuan Guo Yanhong Mi Jiao Yin Zhonghua Du Liming Zhang
Publish Date: 2016/07/09
Volume: , Issue: , Pages: 1-6
Abstract
Sixty Sprague Dawley rats were randomly divided into 6 groups blank group group A model group group B mosapride group group C Muxiang Shunqi Pill 木香顺气丸 MSP group group D SWD lowdose group group E and SWD highdose group group F 10 rats in each group FD rat model was established by clasping rats’ tails for 7 days except the group A After 3 days group A and group B were given distilled water and the medicated rats were given corresponding medicine for 14 days The gastric emptying structure change of ICC in gastric antrum by transmission electron microscope the content of serum NO by nitrate reductant and SCF by enzyme linked immunosorbent assay were observedCompared with group A the rats in group B delayed gastric emptying serum SCF decreased serum NO increased P 005 Compared with group B the rats in groups D E and F were improved on gastric emptying obviously increased on serum SCF decreased on serum NO P 005 and structure change of ICC in gastric antrum improved Compared with group B structure change of ICC of group E after treatment was improved and was closed to group ASupported by the National Natural Science Foundation of China No 81373577 Scientific Research Foundation of Traditional Chinese Medicine of Hunan Provincial Health Department No 2008025 and the Foundation of Changsha Science and Technology Commission No K100106131
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