Authors: Sophie van Rijn Lex Stockmann Martine Borghgraef Hilgo Bruining Conny van RavenswaaijArts Lutgarde Govaerts Kerstin Hansson Hanna Swaab
Publish Date: 2013/07/04
Volume: 44, Issue: 2, Pages: 310-320
Abstract
The present study aimed to gain more insight in the social behavioral phenotype and related autistic symptomatology of children with an extra X chromosome in comparison to children with ASD Participants included 60 children with an extra X chromosome 34 boys with Klinefelter syndrome and 26 girls with Trisomy X 58 children with ASD and 106 controls aged 9 to 18 years We used the Autism Diagnostic Interview Social Responsiveness Scale Social Anxiety Scale and Social Skills Rating System In the extra X group levels of social dysfunction and autism symptoms were increased being in between controls and ASD In contrast to the ASD group the extra X group showed increased social anxiety The effects were similar for boys and girls with an extra X chromosome
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